Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur while taking chloroquine: Incidence not known Some side effects of chloroquine may occur that usually do not need medical attention. Antimalarial plaquenil Hydroxychloroquine monitoring eyes Hydroxychloroquine blog Plaquenil contraindications Sickle cell anemia is caused by a mutation in the gene that tells your body to make the iron-rich compound that makes blood red and enables red blood cells to carry oxygen from your lungs throughout your body hemoglobin. In sickle cell anemia, the abnormal hemoglobin causes red blood cells to become rigid, sticky and misshapen. Several cases of hypopigmentation of the skin have been reported. Most of the patients described were African or of African descent with dark skin who had been exposed to the sun. One was a Hispanic patient who developed vitiligo-like skin depigmentation after 1 month of chloroquine therapy for cutaneous lupus erythematosus. The skin rapidly repigmented after discontinuation of chloroquine therapy. Also, sickle patients have abnormally elevated oxygen consumption anyway, even more so during acute crisis. 24 So, in reality patient status would be worse than our model predicts. Tolerance. Advanced fitness levels are accompanied by tissue adaptations that confer some tolerance to lower capillary pO 2, but sickle patients are not marathon. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. These side effects may go away during treatment as your body adjusts to the medicine. Would chloroquine in a sickle cell patient beh harfmul Older Blood Used in Sickle Cell Transfusions May Be Harmful., Chloroquine Side Effects Common, Severe, Long Term. Hydroxychloroquine side effects fluid retentionPlaquenil side effects muscle weaknessDose of chloroquine phosphate fish tankRituxan interac with plaquenil Sickle Cell Disease and Pregnancy. Sickle cell disease is a blood disorder passed down from parent to child. People with sickle cell disease have abnormal hemoglobin. Hemoglobin is a protein in red blood cells that carries oxygen to the body. Normal red blood cells are smooth, round, and flexible. They look like the letter "O." Sickle Cell Disease and Pregnancy - Health Encyclopedia.. Sickle hemoglobin oxygen affinity‐shifting strategies have.. How is Sickle Cell and Malaria Related? - Health Hearty. Dating With Sickle Cell Can Be a Psychologically Damaging Affair Articles Sickle Cell Diaries February 28, 2018 Gary Swaby Over my years as an adult, I’ve often faced difficulties dating with Sickle Cell. Pain is a common problem for people with sickle cell disease. It happens when the sickle-shaped red blood cells that cause the condition get stuck in small blood vessels and block blood flow. That can cause a pain episode or crisis to start suddenly, usually in the lower back, arms, legs, chest, and belly. Emergency Guide When to See the Doctor. It is very important that every person or family with a child with sickle cell disease has a plan for how to get help immediately, at any hour, if there’s a problem. Fact Sheet Sickle Cell Disease and College. Nine steps to living well with sickle cell disease in college.