Long-term progression of hydroxychloroquine retinopathy off the drug

Discussion in 'Without A Doctor Prescription' started by pirat, 09-Mar-2020.

  1. pilotgya XenForo Moderator

    Long-term progression of hydroxychloroquine retinopathy off the drug


    Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria.

    Chloroquine nightmares How quickly does eye damage progress hydroxychloroquine

    Hydroxychloroquine HCQ, brand name Plaquenil is commonly used for the long-term 2 management of a variety of chronic rheumatic diseases including systemic lupus erythematosus 3 and rheumatoid arthritis. Importance Hydroxychloroquine sulfate is widely used for the long-term treatment of autoimmune conditions but can cause irreversible toxic retinopathy. Prior estimations of risk were low but were based largely on short-term users or severe retinal toxicity bull’s eye maculopathy. The present study reports data on 11 cases of hydroxychloroquine retinopathy that were monitored for 13 to 51 months after cessation of the drug. These cases are identical, with those studied previously with clinical data, although several now have a longer period of follow-up.

    Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Hydroxychloroquine is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus.

    Long-term progression of hydroxychloroquine retinopathy off the drug

    Hydroxychloroquine Side Effects Common, Severe, Long Term., The Risk of Toxic Retinopathy in Patients on Long-term.

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  6. Nevertheless, retinopathy begins to appear with long-term use, and retinopathy is serious insofar as there is no known treatment. It can progress for a year or more after stopping the drug and, if not recognized early at the point of screening, it can lead to functional blindness.

    • Hydroxychloroquine Retinopathy Still Alive and Well - The Rheumatologist.
    • Localization of Damage in Progressive Hydroxychloroquine..
    • Chloroquine retinopathy - Wikipedia.

    The risk of toxic retinopathy in patients on long-term hydroxychloroquine therapy. JAMA Ophthalmol 2014;153–60. Wolfe F, Marmor MF Rates and predictors of hydroxychloroquine retinal toxicity in patients with rheumatoid arthritis and systemic lupus erythematosus. IMPORTANCE Hydroxychloroquine sulfate is widely used for the long-term treatment of autoimmune conditions but can cause irreversible toxic retinopathy. Prior estimations of risk were low but were based largely on short-term users or severe retinal toxicity bull's eye maculopathy. Concomitant renal or liver disease because the drug is cleared by both routes underlying retinal disease or maculopathy ; age greater than 60 years. Monitoring Guidelines. Guidelines on screening for retinopathy associated with hydroxychloroquine toxicity were initially published by the Academy in 2002.

     
  7. TIN Guest

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Immune & Autoimmune - Lupus plaquneil and hair bleaching Does plaquenil cause hair loss? - Coloring my hair while taking generic plaquenil?
     
  8. shoorique New Member

    Plaquenil Uses, Dosage & Side Effects - Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

    Hydroxychloroquine Oral Route Side Effects - Mayo Clinic
     
  9. Osss New Member

    DailyMed - HYDROXYCHLOROQUINE SULFATE tablet Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. Hydroxychloroquine Sulfate film-coated tablets cannot be divided, therefore they should not be used.

    Hydroxychloroquine Plaquenil Toxicity and Recommendations.