Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight. Hydroxychloroquine for ra History of plaquenil Highlights of the 2016 guidelines include the following. Use real body weight. “The bottom line is that the daily dose should be 5.0 mg per kg or less, using real body weight,” said Michael F. Marmor, MD, at Stanford University in Palo Alto, Calif. Plaquenil hydroxychloroquine sulfate, Sanofi-Aventis and the less-used chloroquine are antimalarial drugs with anti-inflammatory properties that are used for the management of a spectrum of inflammatory conditions. Find user ratings and reviews for Plaquenil oral on WebMD including side effects and drug interactions, medication effectiveness, ease of use and satisfaction Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight. Plaquenil 2016 Hydroxychloroquine MedlinePlus Drug Information, How to Succeed in Plaquenil Screenings Does plaquenil weight gainWhat percent of people with arthritis benefit from plaquenilHydroxychloroquine skin rashBilling 120 visual field for plaquenilSides effects of hydroxychloroquine The AAO published dosing and screening recommendations for chloroquine and hydroxychloroquine in 2016, revising previous recommendations published in 2011. The current maximum daily HCQ dose recommended by the AAO is 5 mg/kg of real weight. The 2011 guidelines suggested a maximum dose of 6.5 mg/kg of ideal weight. Despite Plaquenil dosing recommendations, retinal toxicity.. Plaquenil oral Reviews and User Ratings Effectiveness, Ease.. ATIENT NFORMATION ON HYDROXYCHLOROQUINE. For rheumatic diseases, the most common dose is 400 mg per day. In 2016, the previous guideline to keep the daily dose of HCQ under 6.5 mg/kilogram of ideal bodyweight was adjusted to 5 mg/kilogram of the actual body weight to keep the risk of retinopathy within acceptable levels. Abstract. Background The American Academy of Ophthalmology recommendations on screening for chloroquine CQ and hydroxychloroquine HCQ retinopathy are revised in light of new information about the prevalence of toxicity, risk factors, fundus distribution, and effectiveness of screening tools. Oct 30, 2019 Oral 200 to 400 mg daily as a single daily dose or in 2 divided doses. Note Due to the risk of retinal toxicity, do not exceed a daily dose of 5 mg/kg/day using actual body weight or 400 mg, whichever is lower AAO Marmor 2016; Melles 2014; Wallace 2019; Plaquenil labeling 2016.