Earlier recommendations suggested an initial dose of 1 mg/kg/d of prednisone; however, more recent expert opinions endorse a lower dose (eg, 40 mg/d), which is tapered to every-other-day long-term therapy over several weeks. In one study, treatment of acute exacerbations of pulmonary sarcoidosis with steroid doses as low as 20 mg of prednisone for a median of 21 days improved spirometry back to baseline and improved clinical symptoms. Can you take plaquenil at night Canc plaquenil give you ulcers Hydroxychloroquine sulphate bp 200mg Aug 03, 2009 The ATS/ERS/WASOG review suggests an initial dose of 20 to 40 mg/day for pulmonary sarcoidosis, or the equivalent taken alternate days, and further evaluation of response after 1 to 3 months. In steroid responders it advises gradual tapering of the dose to 5 to 10 mg/day or an equivalent alternate day dose. Patients Twelve patients with biopsy-proved sarcoidosis, 6 women and 6 men ranging from 20 to 49 years of age, with neurological involvement. Intervention Chloroquine phosphate, 250 mg twice daily, or hydroxychloroquine sulfate, 200 mg twice daily, was administered for a period of 6 to 21 months. Patients had regular clinical evaluation, determination of serum and cerebrospinal fluid angiotensin-converting enzyme level, computed tomography or magnetic resonance imaging, chest radiography. Oral corticosteroids are the mainstay of treatment for pulmonary sarcoidosis. In a Cochrane review 5 of corticosteroids for pulmonary sarcoidosis, treatment with oral steroids for six to 24 months improved chest radiograph findings compared with placebo. Patients with interstitial lung disease stages II and III. However, data suggest early treatment of stage II sarcoidosis with oral prednisolone for 3 months followed by inhaled budesonide for 15 months improves 5-year pulmonary function and reduces the need for future steroid treatment. Some data suggest that corticosteroid use may be associated with increased relapse rates. Plaquenil for sarcoidosis Taking Plaquenil for Rheumatoid Arthritis, Effectiveness of Chloroquine and Hydroxychloroquine in. Plaquenil toxicity lecturPlaquenil and other medicationsChloroquine 250mg Hydroxychloroquine. As a treatment for sarcoidosis, the antimalarial drug hydroxychloroquine Plaquenil® is most likely to be effective in patients with dermatologic involve-ment, joint manifestations and hypercalcemia. Due to poten-tial macular toxicity, it is recommended that patients on hydroxychloroquine have an eye examination every 6-12 months. SARCOIDOSIS TREATMENT GUIDELINES. Sarcoidosis - American Family Physician. Plaquenil Withdrawal – Life As An Anomaly. Plaquenil was the 1st treatment outside of prednisone that I tried. And I've been on 400 mg from the start. I did fine on it for a quite a while until the sarc joint pain became full fledged rheumatoid arthritis and I had to add something else. Sarcoidosis is a very serious disease if it goes untreated. While many people with sarcoidosis manage well without extensive treatment, chronic illnesses can create a lifelong impact on our bodies. To prevent flare-ups and scarring of your lungs, seek treatment for your sarcoidosis no matter the severity. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.