It gets its name from the coin-shaped lesions it produces. This condition causes a severe rash that tends to get worse when exposed to sunlight. Plaquenil and hearing loss Plaquenil effects on eyes Hydroxychloroquine is the drug of choice when a systemic agent is needed for discoid lupus erythematosus DLE. Chloroquine is second-line antimalarial therapy. Chloroquine and hydroxychloroquine should not be used in combination due to the increased risk of ocular toxicity. Hi everyone, I have Ra and was diagnosed with discoid Lupus last summer. My rheumy juggled my meds and added hydroxychloroquine 200mg. Approx a month after starting this I noticed I was getting more sun sensitive and had a nasty flare which has taken most of the winter to calm down. I have seen dermatologists and they are blaming the discoid Lupus. Hydroxychloroquine is used to treat discoid lupus erythematosus DLE or systemic lupus erythematosus SLE or lupus. It is also used to treat acute and chronic rheumatoid arthritis. This medicine is available only with your doctor's prescription. Severe cases can lead to permanent scarring, hyperpigmentation, and hair loss. The rash can appear anywhere on the body, but you’re likely to see it on the scalp, neck, hands, and feet. Hydroxychloroquine for discoid lupus Hydroxychloroquine I've just been diagnosed with. - LUPUS UK, Hydroxychloroquine ~ sun sensitivity? Hi everyone. - LUPUS UK Why did the price of hydroxychloroquine go up so much Aug 21, 2018 Hydroxychloroquine is the drug of choice when a systemic agent is needed for discoid lupus erythematosus DLE. Chloroquine is second-line antimalarial therapy. Chloroquine and hydroxychloroquine should not be used in combination due to the increased risk of ocular toxicity. Discoid Lupus Erythematosus Medication Antimalarial agents.. Hydroxychloroquine Oral Route Description and Brand Names.. Lupus Medications and Treatments. Hydroxychloroquine is the cornerstone of medical management of systemic lupus erythematosus SLE. It has been shown to prevent flares 1, decrease thrombosis 2 - 5, improve lipids 6, and decrease insulin resistance 7 - 9. Hydroxychloroquine is used to treat rheumatoid arthritis; discoid and systemic lupus erythematosus SLE. Over the long term hydroxychloroquine can reduce pain, swelling and joint stiffness. If you have lupus, it may also improve the rash. It may be as long as 12 weeks before you notice the benefits. In 1956, the U. S. Food and Drug Administration approved HCQ for symptoms of lupus and rheumatoid arthritis, particularly skin inflammation, hair loss, mouth sores, fatigue, and joint pain. Dosing. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight.