Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil and 5hr energy Best alternative to plaquenil With clindamycin in children younger than 8 years and with doxycycline, tetracycline, or clindamycin in children 8 years or older Recommended as a preferred regimen for treatment of uncomplicated malaria due to chloroquine-resistant or unknown resistance P falciparum or species not identified Chloroquine CQ continues to be the first-line medication used worldwide in the treatment of Plasmodium vivax malaria. The dose recommended by the World Health Organization is 25 mg/kg independently of the age of the subject. Nonetheless, the. Chloroquine phosphate or hydroxychloroquine sulfate can be used for prevention of malaria only in destinations where chloroquine resistance is not present see Maps 2-7 and 2-8 or the next section in this chapter, Malaria Risk Information and Prophylaxis, by Country. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine resistant malaria treatment in children Malaria in Children, Evaluation of the paediatric dose of chloroquine in the. Proguanil plus chloroquineHydroxychloroquine plaquenil and pregnancy For treatment of malaria Adults—At first, 1000 milligrams mg once a day. Then, 500 mg 6 to 8 hours after the first dose, and 500 mg on the second and third days of treatment. Adults with low body weight and children—Dose is based on body weight and must be determined by your doctor. Chloroquine Oral Route Proper Use - Mayo Clinic. Malaria Prevention –. Guidelines for Treatment of Malaria in the United States.. Aralen chloroquine is an antimalarial drug used for the treatment of malaria and extraintestinal amebiasis. Common side effects are reduced hearing, tinnitus, nausea, vomiting, and diarrhea. Dosage, drug interactions, and pregnancy and breastfeeding safety are provided. The lower reported “cure” rate in this study reported by parents could imply that chloroquine was being used for cases of falciparum malaria some of which are resistant to chloroquine, and that some of the children may have had a disease other than malaria. The use of herbal medicine was lower than expected. Although chloroquine-resistant P. falciparum predominates in Africa, it is found in combination with chloroquine-sensitive P. vivax malaria in South America and Asia. Resistance of P. vivax to chloroquine has been confirmed only in Papua New Guinea and Indonesia. For destinations where any chloroquine-resistant malaria is present, in addition.