Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. How to take aralen Plaquenil autoimmune neutropenia I looked back through my lab work. Even while taking 400mg of Plaquenil and 15mg of Prednisone also an immunosuppressant, my immune system was still overactive. My Absolute Neutrophils good indicator of immune system function didn't get suppressed to a NORMAL range until I increased the Plaquenil to 600mg/day while still taking the Prednisone. Hydroxychloroquine and the immune system. It is listed as having a mild immunosuppressant effect in my book on RA, but one of the reasons for the blood tests is. IF Plaquinil hydroxychloroquine is an immunosuppressant, shouldn't doctors inform their patients about this as a 'potential' side effect prior to prescribing the drug? This is NOT a litigious query, but an honest question for future patients. My husband's a very intelligent man; he asks questions and talks with his doctors. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Hydroxychloroquine immunosuppressive Is Hydroxychloroquine Plaquenil an Immunosuppressant., Hydroxychloroquine and the immune system Hi everyone. - NRAS Chloroquine and depressionHydroxychloroquine monitoring requirementsWhat are the ingredients in plaquenilWhat is chloroquine tablets used for Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Immunosuppressant drugs. Taking methotrexate. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Do either hydroxychol/Plaquenil put you at risk for.. Hydroxychloroquine. Oct 28, 2015 Infectious diseases have increased the morbidity and mortality in patients with rheumatic diseases because of their natural history or the associated complications such as splenic infarcts and skin ulcers, concomitant chronic diseases, immunosuppressive and immunomodulatory drug use, frequent hospitalization, and surgery. Immunosuppressive effects of hydroxychloroquine and artemisinin combination therapy via the nuclear factor-κB signaling pathway in lupus nephritis mice. Three anti-malarial drugs are prescribed for lupus symptoms. Hydroxychloroquine Plaquenil is the most commonly prescribed because it is generally believed to cause fewer side effects; chloroquine Aralen has a reputation for more serious side effects, but it may be prescribed in situations where hydroxychloroquine cannot be used.