B, Brown pigmentation on the legs in another patient who had systemic lupus erythematosus associated with diffuse discoid lupus. The skin biopsy was performed on the brown area distant from discoid lesions. Hydroxychloroquine 200 mg discount Hydroxychloroquine sulfate monitoring Plaquenil retinal oct Plaquenil eye exam guidelines Amichai B, Gat A, Grunwald MH. Cutaneous hyperpigmentation during therapy with hydroxychloroquine. JCR Journal of Clinical Rheumatology 13 113, No. 2, Apr 2007 - Israel Skin hyperpigmentation is found among people who take Plaquenil, especially for people who are female, 50-59 old, have been taking the drug for 5 - 10 years, also take medication Omniscan, and have Arteriogram Cutaneous hyperpigmentation is a well-known side effect of tetracyclines, but doxycycline-induced cutaneous. during therapy with doxycycline A. Twelve months after stopping doxycycline, the cutaneous. in the lesional skin.5 The role of hydroxychloroquine and its interaction with doxycycline in these cases cannot be B, Presence of iron in the same areas of the dermis (Perls staining, original magnification ×100). Pub Med Google Scholar Crossref Morrison LK, Nordlund JJ, Heffernan MP. Pub Med Google Scholar Costedoat-Chalumeau N, Galicier L, Aumaître O, et al; Group PLUS. Google Scholar Costedoat-Chalumeau N, Amoura Z, Hulot JS, et al. Pub Med Google Scholar Crossref Costedoat-Chalumeau N, Leroux G, Piette J-C, Amoura Z. A, Interstitial and perivascular brown pigmented granules in the dermis (hematoxylin-eosin-safran staining, original magnification ×100). Cutaneous hyperpigmentation during therapy with hydroxychloroquine Persistent cutaneous hyperpigmentation due to., Will you have Skin hyperpigmentation with Plaquenil - eHealthMe Plaquenil prednisonePlaquenil and photosensitivityPlaquenil chplHydroxychloroquine 200 mg acetaminophen 400 mg What is drug-induced skin pigmentation. Drug-induced skin pigmentation accounts for 10–20% of all cases of acquired hyperpigmentation. Pigmentation may be induced by a wide variety of drugs; the main ones implicated include non-steroidal anti-inflammatory drugs NSAIDs, phenytoin, antimalarials, amiodarone, antipsychotic drugs, cytotoxic drugs, tetracyclines, and heavy metals. Drug-induced hyperpigmentation DermNet NZ. CASE REPORT Cutaneous hyperpigmentation induced by.. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Background Hydroxychloroquine sulfate and other antimalarial drugs have been used successfully as adjunctive therapy for patients with cutaneous lesions of dermatomyositis over the past 20 years. An increased incidence of cutaneous reactions to hydroxychloroquine has been postulated to occur in patients with dermatomyositis. Skin Hyperpigmentation with Hydroxychloroquine. Hydroxychloroquine Plaquenil is a common trade name is an anti-inflammatory oral medication that is commonly used to treat many autoimmune diseases. In the hair clinic, we use it for diseases such as lichen planopilaris, frontal fibrosing alopecia, pseudopelade and discoid lupus. An elderly woman presented with 6 months history of skin coloured to erythematous papules in annular pattern over extremities, upper back and neck. The patient was diagnosed with granuloma annulare GA and started on hydroxychloroquine HCQ 300 mg daily. After 4 months of treatment, she developed bluish grey pigmentation within the plaques of GA with normal surrounding skin figure 1A,B.