Yesterday my rheumatologist started me on hydroxychloroquine as well. Is anyone else on this combination and have you had any problems with it as I know hydroxychloroquine can cause eye sight problems. Plaquenil a preventive medicine Should users of hydroxychloroquine take cholesterol-lowering medications Chloroquine malaria price Hydroxychloroquine lupus life insurance I had to stop methotrexate about 7 months ago for my RA, due to bad side effects after using it successfully for 10 years. As an alternative, my rheumy put me on HCQS, also known as plaquenil, along with 5mg of prednisone. But ever since then I've had the runs something terrible, and whatever I do or don't do I can't seem to shake it. Plaquenil hydroxychloroquine belongs to a group of medicines called quinolines. Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Learn when your doctor might switch you to one of these drugs, and how to make the change. like methotrexate, sulfasalazine, hydroxychloroquine, or leflunomide. Recently my eyes have felt sore and, after posting a question on this site, I am seeing my GP on Monday. Thanks Hi Catjones I have been taking this combination, started on both of them in January this year. How to switch from plaquenil to methotrexate Which would you pick and why? - Plaquenil or Methotrexate, Plaquenil Uses, Dosage & Side Effects - Plaquenil macular edema Hydroxychloroquine brand namePlaquenil is a disease-modifying anti-rheumatic drug DMARD approved for adults with RA. It is often given in combination with methotrexate and sulfasalazine a treatment known as triple therapy, to help slow RA disease progression for patients who do not get relief from methotrexate therapy alone. 1,2 Hydroxychloroquine Plaquenil -. How You Can Work With Your Doctor to Switch Your RA Meds. Methotrexate and its benefit for Sjögren’s patients. Methotrexate or Plaquenil. Methotrexate is the most commonly prescribed DMARD, but it does come with the chance of side-effects. I never had any side-effects of dire consequence, but many on this forum have. Methotrexate may take longer to become effective, but USUALLY, it will take effective within the time frame you're looking at. This is a really good article. I am on Plaquenil and Methotrexate. We tried Enbrel for a year, then had to switch to Remicade. Still not working well, we have increased the dosage twice. I am on Prednisone 5mg just as a temporary measure until I go back next week. It is time to move on, but I couldn’t decide between Rituxin, Acterma, or Orencia. O’Dell JR et al. 2002 “Treatment of rheumatoid arthritis with methotrexate and hydroxychloroquine, methotrexate and sulfasalazine, or a combination of the three medications results of a two-year, randomized, double-blind, placebo-controlled trial” Arthritis Rheum May;4651164-70.