I can say that the prednisone wean was successful, even after having only been on plaquenil a few months. To answer some of your other questions, it was the same timeframe for me. Chloroquine phosphate uses Malaria drug combined mice chloroquine 17 The most common side effects are nausea and diarrhea, which often improve with time. Less common side effects include rash, changes in skin pigment such as darkening or dark spots, hair changes, and muscle weakness. Aug 14, 2017 Plaquenil can cause serious side effects when used in high doses for chronic diseases such as RA over the long term. The New Zealand Dermatological Society recommends that to decrease the risk of retina damage, no more than 200mg of Plaquenil should be taken a day, and a dose of 400mg per day should be taken no longer than a few weeks. If common side effects do occur, they are usually minor and last only for a short period of time. Please note the rare side effects listed below, specifically retinopathy, which causes damage to the eyes. Side effects associated with Plaquenil are placed in three categories common. But I couldn't handle the heart issue and not being able to breathe (plus all the other pains). Yesterday would've been my 4th day at the reduced dose. Plaquenil withdrawal side effects Plaquenil oral Reviews and User Ratings Effectiveness., Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis. Plaquenil active ingredientsThe looks of a plaquenil pillPlaquenil ocular screeningChloroquine overdose dosagePlaquenil tylenol Serious side effects and their symptoms can include the following blurred vision or other vision changes. ringing in your ears or hearing loss. angioedema, or rapid swelling of your skin. hives. mild or severe bronchospasm that causes trouble breathing. sore throat. unusual bleeding or bruising. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus. Stopping plaquenil. DailyStrength. Of the six patients withdrawn from the study because of a severe exacerbation of disease activity, a single patient in the hydroxychloroquine group and two in the placebo group were withdrawn because of severe exacerbations of polyarthritis, constitutional conditions, or mucocutaneous manifestations. Serious Side Effects of Plaquenil. If you are taking Plaquenil long-term, such as for an autoimmune condition, your doctor should regularly check you for potential serious side effects. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember.