The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Hydroxychloroquine is used as disease modifying anti-rheumatic drug (DMARD) for treatment of several autoimmune diseases, such as systemic lupus erythematosus (SLE), rheumatoid arthritis(RA) for more than one century. Listing a study does not mean it has been evaluated by the U. The purpose of this study is to evaluate whether hydroxychloroquine is effective in treatment of Hashimoto's thyroiditis. Chloroquine phosphate wrasse Chloroquine mammalian cells Starting plaquenil These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about. The aforementioned rare side effect that affects vision hydroxychloroquine retinopathy, if caught early, may improve after discontinuation of Plaquenil. Since the side effect of vision loss is possible but rare, it is important for you to tell your doctor about any vision changes that you experience. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase G-6-PD deficiency. Take Plaquenil for the full prescribed length of time for malaria. Your symptoms may improve before the infection is completely cleared. Hashimoto's thyroiditis is an autoimmune thyroid disease, and when the disease progresses, thyroid function finally declined to hypothyroidism. Hashimoto's thyroiditis is an autoimmune thyroid disease, which induced chronic inflammation of thyroid gland and destroys thyroid tissue. Can plaquenil affect your thyroid Plaquenil and Autoimmune Thyroid Disease - Reviews, Taking Plaquenil for Rheumatoid Arthritis Chloroquine authophagyChloroquine phosphate reef centralChloroquine endosomal escapePlaquenil as it affects the eyes symptoms Even taking your thyroid meds differently can change your level. Are you taking the thyroid meds first thing in the morning at least one hour before food or brushing your teeth. The other suggestion would be to try taking your plaquenil one with breakfast and one with dinner or night time snack. Increasing plaquenil, having problems. Plaquenil Uses, Dosage & Side Effects -. Long-Term Side Effects of Plaquenil for Rheumatoid Arthritis.. Corticosteroids Can Also Affect The Health Of The Adrenal Glands In addition to affecting the thyroid gland, corticosteroids also can affect the health of the adrenal glands. The reason for this is because the adrenal glands secrete cortisol, which of course is a natural steroid hormone of the body. This gland produces hormones that regulate your body’s energy use, along with many other important functions. Hypothyroidism is when the thyroid is underactive. When thyroid hormone production drops, your body’s processes slow down and change. Hypothyroidism can affect many different systems in your body. Even sips of coffee can affect your thyroid medication if the two aren’t spaced apart enough. In studies, coffee reduced the body’s absorption of thyroid medications by about 30%. That’s why experts recommend that you wait at least 60 minutes after drinking coffee to take your thyroid replacement medication.