A, At the start of hydroxychloroquine sulfate treatment. B, Two years after starting treatment, a right paracentral scotoma appeared. Eye test plaquenil Plaquenil and prednisone for ra Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Central threshold automated visual fields with a white target • Subtle, repeatable visual field defectsshould be taken seriously and are an indication to do objective testing At least one of the following objective tests should be performed during routine screening if available19 Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Morand EFMc Cloud PILittlejohn GO Continuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis. C, Three years after cessation of treatment, the scotoma regressed. Plaquenil visual field defect Hydroxychloroquine Plaquenil Toxicity and., Early Plaquenil Toxicity Detected without Bull’s Eye Maculopathy Plaquenil liver side effectsPlaquenil and lung cancer SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Chloroquine retinopathy - Wikipedia. Will you have Visual field defect with Plaquenil - eHealthMe. Nov 18, 2011 Although visual field defects in HCQ toxicity can be highly variable in terms of the depth of defect, all our patients showed a similar pattern on 10-2 white, with the same areas affected. However, one needs to look carefully for subtle decreases in threshold in the area at risk 2–6 degrees from center. The most frequent regions of the retina showing early damage are inferotemporal, with a corresponding superonasal field defect, but this is not absolute. Uncertain visual field changes should trigger retesting for consistency or evaluation with other objective tests, such as mfERG which measures the field electrically, SD OCT, and FAF. If you simply cannot get a visual field due to patient cooperation or attention, you can order an optic nerve OCT to follow the optic nerve head objectively though thinning does not always necessarily correlate to field loss. 2 Superior / inferior arcuate defect. The most common early to mid stage glaucomatous field.