While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. "I was on this hydroxychloroquine for 6 months and then suddenly developed severe itching (burning like sensation, worse than any itch I have ever had) and rash that went from my neck to my feet. Hydroxychloroquine and peripheral neuropathy Chloroquine tablets boots Last August I decided to retire due to fatigue and joint pain. Plaquenil does relieve much of the fatigue. As for the joint pain, still a problem. Yes, depression is an issue, still is. The form of meditation I practice is called Mindfulness Based Stress Reduction and daily practicing helps relieve the symptoms of depression. Has anyone's doctor suggested Plaquenil for chronic fatigue syndrome? My rheumy has a couple of times. He says it could help with energy level because it is an immune enhancer. My mother took it for rheumatoid arthritis years ago and thinks it's worth a shot. My only concern is the. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. I'm not completely pain free, but it's a lot better than it was. I've been on plaquenil since mid June I have had a lot of stress in my life so I can't determine what is causing what. Not seeing any improvements with pain but I just went to 0 prednisone 3 weeks ago. said give it a few months and if I don't see any improvement I might as well go off of it. Wanted to let you know that I was on plaquenil for about three years and I told my RA doctor that my fatigue was worse. Hi everyone, I am wondering if anyone has had a problem with fatigue while on Plaquenil. At first, I was nauseous for a week or so, which the dr. After the nausea went away it seemed like my pain got worse for a week or so, and then it gradually got better. I am also bothered with stomach cramps and mild diarrhea. How does plaquenil help with fatigue Plaquenil pros and cons - Sclero Forums MAIN - Sclero Forums, Plaquenil for CFS. ProHealth Fibromyalgia, ME/CFS and. Chloroquine cathepsinPlaquenil macular degenerationIs plaquenil compatible with omega 3 fish oilHydroxychloroquine urine color Plaquenil is a unique drug that helps control/suppress certain autoimmune symptoms. Plaquenil will not work for everyone with autoimmune issues. But there are other drugs like Erythromycin, Azithromycin, Doxycycline, Fluconazole, Malarone, ect. that may work better for your autoimmune condition. Hydroxychloroquine User Reviews for Systemic Lupus.. Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses. Hydroxychloroquine Reviews Everyday Health. I thought fatigue is one of the symptoms of RA, so taking the right medication should help lessen fatigue, shouldn't it? When I was diagnosed with RA 2.5 years ago, I experienced fatigue and really bad pain on my foot, but since I started Plaquenil and Orencia 2 years ago, I have been in medically induced remission and don't have fatigue anymore. All since then I've been tested and diagnosed. Today my rheumy decided to go ahead and prescribe plaquenil. My main issues are joint, muscle and tendon pain/inflammation,As well as fatigue. Besides my possible heart and lung involvement My doc said plaquenil will help with the pain and inflammation. Will it help with the fatigue? Dr. Krauser responded Yes. Fatigue is the result of the inflammation. If Plaquenil hydroxychloroquine works, it will also help the fatigue.