The toxicities can be grouped into categories such as pigmentary retinopathies, crystalline retinopathies, retinal vasculopathies, and retinopathies characterized by retinal edema or folds. Here we present a case of topiramate (Topamax, Ortho-Mc Neil Neurologics) causing transient angle closure and retinal folds. Chloroquine for research Plaquenil target Plaquenil Toxicity Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. Download PDF. Drug-induced ocular side effects are back in the spotlight, thanks to the Academy’s revision of its recommendations on screening for retinal toxicity from chloroquine and its analogue hydroxychloroquine Plaquenil. 1 There are hundreds of drugs with potential retinal toxicity—so many that the National Registry of Drug-Induced Ocular Side Effects doesn’t stratify them by. Diagnosis Hydroxychloroquine-induced retinal toxicity Discussion. Chloroquine CQ and hydroxychloroquine Plaquenil HCQ have been used for many years, initially for the treatment of malaria but now more commonly for the treatment of inflammatory diseases such as rheumatoid arthritis and lupus 1. It is now considered for new disease applications in diabetes, heart disease and adjunct cancer therapies 2. A 26-year-old woman reported to the emergency room with a chief complaint of sudden, painless loss of vision in both eyes. We follow with a review of the literature regarding topiramate toxicity, as well as a brief review of the other major categories of pharmacologic retinal toxicity. Plaquenil induced retinal toxicity H35.381-383 Toxic Maculopathy Of Retina - Decision-Maker PLUS, Rx Side Effects New Plaquenil Guidelines and More. Plaquenil anti inflammatory mechanismHydroxychloroquine and tattoosHydroxychloroquine eyes treatmentMethotrexate and plaquenil for ra A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a Patient with Recent Onset of Renal Impairment A Review of the Literature on the Use of Hydroxychloroquine in Renal Impairment. Rajen Tailor, * Ibrahim Elaraoud, Peter Good, Monique Hope-Ross, and Robert A. H. Scott A Case of Severe Hydroxychloroquine-Induced Retinal.. Hydroxychloroquine Plaquenil Toxicity and.. A Case of Severe Hydroxychloroquine-Induced Retinal Toxicity in a.. Rheumatologists use hydroxychloroquine sulfate Plaquenil, Concordia Pharmaceuticals to treat autoimmune diseases, namely discoid or systemic lupus erythematosus, rheumatoid arthritis, Sjögren syndrome, and malaria. When taken at high doses and for long durations, hydroxychloroquine has been known to cause parafoveal retinal toxicity. Plaquenil hydroxychloroquine is a medicine commonly used to treat patients with systemic lupus erythematosus and rheumatoid arthritis. After prolonged use, it can sometimes damage the macula and cause central vision loss. Typically, the macula loses its orange pigment, giving the appearance of a bullseye. Although the incidence of macular toxicity is infrequent with Plaquenil use at a dosage of 200mg or 400mg q.d. its visual impact can be devastating. 2,3. The associated classic retinal toxicity is described as a bull’s eye maculopathy ring of depigmented retinal pigment epithelium that spares the foveal area.