Alternatively, we suggest using this opportunity to take a little break from work and read some of the interesting articles below. Summary Chloroquine is an anti-malarial drug available at pharmacies for people traveling to area with malaria risks. Plaquenil vs tacrolimus Chloroquine malaria prophylaxis Plaquenil pyroderma Apr 11, 2012 Chloroquine as an Anti-autophagic Radiosensitizing Drug in Stage I-III Small Cell Lung Cancer Chloroquine The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. Autophagy and cancer. A large body of evidence suggests that the relationship between autophagy and cancer is complex.42, 43 On the one hand, autophagy appears to inhibit malignant transformation, reflecting its capability to limit the accumulation of potentially oncogenic entities like depolarized mitochondria which overproduce potentially genotoxic reactive oxygen species, ROS. Strange as it may sound, but it is true. Yes, this is what a group of researchers from Harvard Medical School recently reported in a reputed journal. I believe most of us especially those living in India and Africa, are well aware of Chloroquine, which is known as one of the most widely and successfully used first generation anti-malarial drug. It is one of very few available drugs that inhibits autophagy, a mechanism associated with its anticancer properties. Note: based on a RGCC chemosensitivity analysis I have seen at a German clinic, Hydroxychloroquine has been effective in killing the cancer cells of 5 out 7 patients that were tested. Chloroquine lung cancer Cancers Free Full-Text Combination Therapy of Chloroquine., Chloroquine and hydroxychloroquine for cancer therapy Back pain and stiffness plaquenilWhen does plaquenil start working To investigate the effects of chloroquine diphosphate CQ on lung cancer cell growth, we treated A549 cells, a lung cancer cell line, with the drug at various concentrations 0.25–128 μM for 24–72 h. Chloroquine inhibits cell growth and induces cell death in.. Chloroquine and Cancer Treatment - Biomedical Research, A.. Chloroquine inhibits cell growth in human A549 lung cancer.. Vaidya Atreya Smith is the director for the European Institute of Vedic Studies located in Switzerland. He has been practicing more than 25 years and has lived and studied in India from 1987 to 1994. In 2005 he was awarded the title of Vaidya in Varanasi, India. The NCI Drug Dictionary contains technical definitions and synonyms for drugs/agents used to treat patients with cancer or conditions related to cancer. Each drug entry includes links to check for clinical trials listed in NCI's List of Cancer Clinical Trials. Non-small cell lung cancer NSCLC is a type of malignant cancer, and 85% of metastatic NSCLC patients have a poor prognosis. C 2-ceramide induces G2/M phase arrest and cytotoxicity in NSCLC this study, the autophagy-inducing effect of C 2-ceramide was demonstrated, and cotreatment with the autophagy inhibitor chloroquine CQ was investigated in NSCLC H460 and H1299 cells.