Also acts as an inhibitor of autophagy and toll-like receptor (TLR) 7/9. Hydroxychloroquine Sulfate is a potent inhibitor of autophagy. Chloroquine lysosomal degradation Plaquenil toxicity oct images Plaquenil side effects depression Name Hydroxychloroquine sulfate Drug Entry Hydroxychloroquine. Hydroxychloroquine is a racemic mixture consisting of an R and S enantiomer. 2 Hydroxychloroquine is an aminoquinoline like chloroquine. 8 It is a commonly prescribed medication in the treatment of uncomplicated malaria, rheumatoid arthritis, chronic discoid lupus erythematosus, and systemic lupus erythematosus. 8. Hydroxychloroquine Sulfate is an antimalarial agent used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune, inflammatory and dermatologic conditions. Also acts as an inhibitor of autophagy and toll-like receptor TLR 7/9. Sep 01, 2019 The molecular weight of hydroxychloroquine sulfate is 433.95, and molecular formula is C 18 H 26 ClN 3 O. H 2 SO 4. Each hydroxychloroquine sulfate tablet intended for oral administration contains 200 mg of hydroxychloroquine sulfate equivalent to 155 mg base. HCQ treatment inhibits RCC (renal cell cancer) cell growth, promotes apoptosis, inhibits mitochondrial oxygen consumption, and increases rates of glycolysis In vitro kinase assays: with purified proteins, recombinant S6 protein and recombinant active P70S6K are incubated in 1x kinase buffer with various amount of HCQ or RAD001 in the presence (25 μM) or absence of ATP for 30 minutes at 30°C. It prevents lysosomal acidification, thereby interfering with a key step in the autophagic process. Hydroxychloroquine sulfate molecular weight SAFETY DATA SHEET Page 1 of 5 Hydroxychloroquine sulfate., Hydroxychloroquine Sulfate Autophagy inhibitor Read. Coppolino quarantine chloroquine May be stored at RT for short-term only. Long-term storage is recommended at 4°C. Stable for 6 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Hydroxychloroquine Sulfate CAS. Hydroxychloroquine Tablets - FDA prescribing information.. Hydroxychloroquine - Wikipedia. CAS 747-36-4 Molecular Formula C 18 H 26 ClN 3 OH 2 SO 4 Molecular Weight g/mol 433.96 MDL Number MFCD00078203 InChI Key JCBIVZZPXRZKTI-UHFFFAOYSA-N Synonym hydroxychloroquine sulfate,hydroxychloroquine sulphate,ercoquin,plaquinol,toremonil,2-4-7-chloroquinolin-4-yl amino pentyl ethyl amino ethanol sulfate,hydroxychloroquine sulfate usp,plaquenil tn,hydroxychloroquine; sulfuric. Compound Hydroxychloroquine sulfate with free spectra 1 NMR, 1 FTIR, and 1 Raman. Hydroxychloroquine C18H26ClN3O CID 3652 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities.