Hydroxychloroquine is a one of a number of drugs which have been used for many years in the treatment of malaria. Fortunately, it was discovered these drugs often are helpful in the treatment of various rheumatic diseases, particularly systemic lupus erythematosus (SLE or "Lupus") and rheumatoid arthritis. Plaquenil for ulcers Precautions of chloroquine Chloroquine aralen My dr told me that she thinks that I probably have Fibromyalgia and an Undifferentiated Connective Tissue Disorder suspected Lupus. She gave me Plaquenil for the pain that I have been having, and a steroid pack in the interm. User Reviews for Hydroxychloroquine to treat Systemic Lupus Erythematosus. Also known as Plaquenil, Quineprox. The following information is NOT intended to endorse any particular medication. While these reviews might be helpful, they are not a substitute for the expertise, skill, knowledge and judgement of healthcare practitioners. Overview. Fatigue. Systemic weakness is a state that usually follows lupus flare-ups. In the case of possible drug interaction, CBD oil can be used solitary for total system recovery. Homeostasis maintenance is the link between CBD oil and lupus fatigue treatment. This is based on the anti-anxiety effects of CBD. When effective, it can decrease damage to the tissues of the joints, skin and other organs in the body. Although chloroquine is sometimes used, the preferred antimalarial drug is hydroxychloroquine due to its greater safety. It is not possible at the present time to explain precisely why hydroxychloroquine is effective in various rheumatic diseases. Plaquenil for lupus reviews fatigue Is extreme fatigue a side effect of Plaquenil?, Hydroxychloroquine User Reviews for Systemic Lupus. Chloroquine injection routeMethotrexate and hydroxychloroquine for rheumatoid arthritisChloroquine how to sayDifference between hydroxychloroquine and chloroquineHydro chloroquine For the first year I started with only 200 mg plaquenil and large doses of sodium salicylate this drug is no longer used and is like giant horse pill aspirin After that, I only took 200 Plaquenil for 14 years. I am now on several medications for lupus and other things. Plaquenil takes several months to become effective. Best medication to treat Lupus fatigue?" Lupus Community.. CBD and Lupus — All You Need to Know in 2020. Strategies for managing fatigue Lupus Foundation of America. I am 99% sure that the Plaquenil has not caused your fatigue. If anything, it’s Lupus OR psychosomatic. Plaquenil is a slow-acting drug which is why you take it long term. It honestly takes on average 1 to 3 months to work and be built up in your system, which is why you typically have a 3-6 month review after being prescribed it. I think that Plaquenil helped me with fatigue althjough I can still sleep for 12 hours straight at a weekend. 200mg Plaq didn't help - 400md did. It took at least 6 months for me to notice a difference. Taking thyroid meds as well may have helped in my case - but I think it helped more with depression. These medications may also prevent lupus from spreading to certain organs, such as the kidney and central nervous system your brain and spinal cord and may help to reduce flares by as much as 50%. Plaquenil and other anti-malarials are the key to controlling lupus long term, and some lupus patients may be on Plaquenil for the rest of their lives.