This medicine is also sometimes given off-label to help the following conditions: Also, let your doctor know if you drink large amounts of alcohol before starting on this medicine. Your doctor will probably want to order frequent tests to check your body's response to chloroquine. Plaquenil discontinuation syndrome Plaquenil and sulfasalazine combination Indication of chloroquine in pregnancy Feb 19, 2020 Taking hydroxychloroquine long-term or at high doses may cause irreversible damage to the retina of your eye. Stop taking hydroxychloroquine and call your doctor at once if you have trouble focusing, if you see light streaks or flashes in your vision, or if you notice any swelling or color changes in your eyes. A few years ago my eye doctor noticed an issue on the exam, and I noticed peripheral vision damage and glare issues. He immediately same day called my rheumatologist, who took me off plaquenil. My eye doc said it was the first case he had seen where there was an effect. If you take Plaquenil for your inflammatory disease, your ophthalmologist will check for damage to the retina in the back of the eye while you take the drug. Let your healthcare provider know if your symptoms either don't improve or worsen while taking this medicine. Keep all appointments with your doctor and laboratory. Chloroquine eye damage Hydroxychloroquine Plaquenil Toxicity and Recommendations., Has anyone experienced plaquenil toxicity with damage to eyes? Plaquenil wbc5 years for plaquenil to leave eyeRheumatoid arthritis medication plaquenil Plaquenil Side Effects by Likelihood and Severity INFREQUENT side effects. If experienced, these tend to have a Severe expression. A Disorder Of The Retina Of The Eye; Common and Rare Side Effects for Plaquenil Oral. How Do Ophthalmologists Look for Plaquenil Damage.. Conditions Plaquenil-related Eye Problems Eugene Eye Care. Aug 14, 2017 This means many people taking Plaquenil for RA are taking a dose of 400mg a day or higher. Pigment deposits in the retina can cause vision changes, according to Steven Ofner, M. D. of Eugene Oregon Eye Care. Signs of retinal damage include blurry or distorted vision, flashes of light or floaters, or loss of night vision. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Eye damage risk. Using this drug for a long time. This toxicity affects a part of the eye called the retina and can lead to color blindness and even loss of vision. An ophthalmologist eye specialist often can detect changes in the retina that suggest toxicity before serious damage occurs. Therefore, regular eye examinations, even when there are no symptoms, are mandatory.