The patient experienced a ventricular tachycardia leading to cardiac arrest and was found to have a prolonged QT interval. Although citalopram is eliminated more slowly in patients with mild to moderate renal impairment a dose adjustment is not necessary. However, no information is available on treatment of patients with severely reduced renal function and prescribers are advised to use caution. Retinal deposits plaquenil Is hydroxychloroquine sulfate an immune suppressing drug Plaquenil and melatonin Plaquenil common side effects Summary Long qt syndrome is found among people who take Plaquenil, especially for people who are female, 60+ old also take medication Quinine, and have Muscle spasms. This study is created by eHealthMe based on reports of 48,911 people who have side effects when taking Plaquenil from Food and Drug Administration FDA. For citalopram doses of 40 mg/day, prolongation of the corrected QTc interval was estimated to be 12.6 ms. 5 For reference, increases in QTc to ≥ 500 ms or a drug -induced increase from baseline of ≥ 60 ms would represent significant changes in clinical trials. List of Drugs to be Avoided by Patients with Congenital Long QT Syndrome LQTS* updated July 2013 *This list is not comprehensive but is meant to be a practical list for those clinicians managing patients with LQTS in Canada. QT prolongation is a measure of delayed ventricular repolarisation, which can cause Torsades de Pointes, ventricular tachycardia, and sudden death. In elderly patients, patients with reduced hepatic function, patients who are CYP2C19 poor metabolisers, and patients taking CYPC19 inhibitors (eg, cimetidine and omeprazole), the maximum dose should not exceed 20 mg a day because these factors lead to increased blood levels of citalopram. Plaquenil and citalopram qt prolongation Drug-drug interactions and QT prolongation as a commonly., Citalopram-induced QTc prolongation A brief review of the. Chloroquine dosing in infantsMarine chloroquine phosphateSarafen and plaquenilPrecautions of chloroquine Cases of QT prolongation and ventricular arrhythmia, including Torsade de Pointes TdP, have been reported via the Yellow Card Scheme with citalopram and escitalopram, mainly in women, those with hypokalaemia, or in those with pre-existing QT prolongation or other cardiac diseases. Citalopram and escitalopram QT interval prolongation - GOV. UK. List of Drugs to be Avoided by Patients with Congenital Long.. Escitalopram and QTc prolongation. Citalopram/QT Prolonging Agents Interactions. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Cardiac Effects, including Cardiomyopathy and QT prolongation Postmarketing cases of life-threatening and fatal cardiomyopathy have been reported with use of Plaquenil as well as with use of chloroquine. Patients may present with atrioventricular block, pulmonary hypertension, sick sinus syndrome or with cardiac complications. A recent clinical study found that citalopram is associated with a dose dependent increase in the risk of QT prolongation 1. QT prolongation is an established side effect of Class I and Class III antiarrhythmic medicines and a rare side effect of a wide range of other medicines that lead to cardiac dysrhythmia.