It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Plaquenil difficulty sleeping How chloroquine icauses itch It is licensed in the UK for the treatment of malaria. Hydroxychloroquine is particularly effective for systemic lupus erythematosus SLE and discoid lupus erythematosus DLE. By reducing inflammation, hydroxychloroquine can decrease pain, swelling and stiffness of joints, and improve or clear some rashes. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Topical treatments are also a standard part of cutaneous lupus therapy. Topical corticosteroids, such as triamcinolone or clobetasol, are available in a variety of doses and forms including creams, ointments, lotions, sprays, and shampoos to treat cutaneous lupus lesions or rashes just about anywhere on the body. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. How to treat plaquenil rash Treating Lupus with Anti-Malarial Drugs Johns Hopkins Lupus., Plaquenil Hydroxychloroquine - Side Effects, Dosage, Interactions - Drugs Chloroquine toxicity doseHydroxychloroquine plaquenil wikipediaPlaquenil drug usesSeroqul and chloroquin If you definitely cannot take the plaquenil, then you should speak with your rheumy about starting may make you start to feel better. There are other anti-malaria drugs on the market that your rheumy can put you on instead of the plaquenil. But, make sure the he/she is convinced that you are actually allergic to the plaquenil. Allergic reaction to plaquenil DailyStrength. How to Treat and Prevent Lupus Rash Living with Cutaneous.. Immune & Autoimmune - Lupus Anyone Get An Itchy Rash From. I wouldn't restart the plaquenil with the rash you have, I would ask for the biopsy or to see a dermatologist. The other possibility is that your liver didn't process the med well, however it is the standard med to start treating Lupus with. I hope they get it under control soon. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more.