Plaquenil daily dose to minimize retinopathy

Discussion in 'Aralen 250 Mg' started by FloydGP, 02-Mar-2020.

  1. MiddleSky2 XenForo Moderator

    Plaquenil daily dose to minimize retinopathy


    Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology.

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    The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Doses above 400 mg a day are not recommended. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Mg PO daily in a single or divided dose tablets are 200 mg. To reduce the risk of retinopathy, do not exceed 5 mg/kg/day or 400 mg PO daily. DOSE ADJUSTMENT. Hydroxychloroquine is generally considered to be the safest DMARD, and a “go to” drug for pregnancy.

    While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula.

    Plaquenil daily dose to minimize retinopathy

    Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Drug spotlight on hydroxychloroquine Lupus Foundation of.

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  3. May 02, 2018 Evidence from a large-scale clinical trial found that the risk of developing retinopathy for individuals using a daily dose ≤5.0 mg/kg was less than 1% in the first 5 years of therapy and less than 2% up to 10 years of use. 2 The panel recommended a daily dosage of 5.0 mg/kg real weight. It is important to note ideal weight formulas may.

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    Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Because early toxicity changes can be revealed on SD-OCT, it is prudent to perform a baseline screening of patients taking Plaquenil. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. The risk of retinal damages is small with daily doses of up to 6.5 mg/kg body weight. Exceeding the recommended daily dose sharply increases the risk of retinal toxicity. This examination should be more frequent and adapted to the patient in the following situations daily dosage exceeding 6.5 mg/kg ideal body weight.

     
  4. Cool'eR Moderator

    https:// an appt with my LLMD, who told me of this recent study.is a well known LLMD who has used this as part of his pulsing protocol for awhile (liposomal type of Oo O)..made me herx and brought me back to good health, for awhile at leastvery interesting it was liposomal oil of oregano, by prescription, from hopkinton drug, a compounding pharmacy in Massachussets- it was sent by mail in a cold pack..i would imagine non liposomal variety over the counter may work as well yes i've heard of several LLMD's using liposomal Oo O. Plaquenil side effects? - @Kristi83 - Arthritis - 20160713. Babesia Testing and Treatment – Suzy Cohen suggests ways to heal. Natural Treatments for Lupus - Earth Clinic
     
  5. ironmaiden Well-Known Member

    Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out.

    Hydroxychloroquine Plaquenil thread COVID19
     
  6. adaksdesk XenForo Moderator

    Discoid Lupus Rash Symptoms, Treatment, and Causes Discoid lupus should not be confused with systemic lupus. Systemic lupus can also cause a mild rash, usually on the face, but it also affects the internal organs. A person with systemic lupus can.

    Lupus & Plaquenil/Pain -