Chloroquine is now uncommonly used in favor of its derivative hydroxychloroquine. In the United States, hydroxychloroquine is most often used for its anti-inflammatory effects in rheumatology and dermatology. Plaquenil and dry mouth Can you donate blood if you are taking hydroxychloroquine Plaquenil singapore Chloroquine phosphate syrup dosage The recommended adult dosage is 200 to 400 mg 155 to 310 mg base daily, administered as a single daily dose or in two divided doses. Doses above 400 mg a day are not recommended. The incidence of retinopathy has been reported to be higher when this maintenance dose is exceeded. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day. Mg PO daily in a single or divided dose tablets are 200 mg. To reduce the risk of retinopathy, do not exceed 5 mg/kg/day or 400 mg PO daily. DOSE ADJUSTMENT. Hydroxychloroquine is generally considered to be the safest DMARD, and a “go to” drug for pregnancy. While early toxicity may be asymtomatic, patients with more advanced stage of toxicity may complain of color vision changes or paracentral scotomas. Its toxic effects on the retina are seen in the macula. Plaquenil daily dose to minimize retinopathy Plaquenil Hydroxychloroquine Uses, Dosage, Side Effects., Drug spotlight on hydroxychloroquine Lupus Foundation of. Chloroquine resistant malaria cdc May 02, 2018 Evidence from a large-scale clinical trial found that the risk of developing retinopathy for individuals using a daily dose ≤5.0 mg/kg was less than 1% in the ﬁrst 5 years of therapy and less than 2% up to 10 years of use. 2 The panel recommended a daily dosage of 5.0 mg/kg real weight. It is important to note ideal weight formulas may. This is Why You Need Multifocal ERG if You Have Plaquenil.. Hydroxychloroquine Plaquenil RheumTutor. Hydroxychloroquine Retinopathy Still Alive and Well - The.. Hydroxychloroquine sulfate HCQ, Plaquenil is an analogue of chloroquine CQ, an antimalarial agent, used for the treatment of systemic lupus erythematosus, rheumatoid arthritis and other autoimmune disorders. Its use has been associated with severe retinal toxicity, requiring a discontinuation of therapy. Because early toxicity changes can be revealed on SD-OCT, it is prudent to perform a baseline screening of patients taking Plaquenil. Multifocal ERG has the ability to detect early macular dysfunction, so it should be included as part of baseline screening. A maximum daily dose of Plaquenil of 5.0mg/kg real weight is recommended. The risk of retinal damages is small with daily doses of up to 6.5 mg/kg body weight. Exceeding the recommended daily dose sharply increases the risk of retinal toxicity. This examination should be more frequent and adapted to the patient in the following situations daily dosage exceeding 6.5 mg/kg ideal body weight.