Hydroxychloroquine is available as the brand-name drug Plaquenil. Generic drugs usually cost less than the brand-name version. Hydroxychloroquine may be used as part of a combination therapy. Plaquenil used for psoriasis Do i need prescription for chloroquine phosphate Plaquenil hydroxychloroquine and Rheumatrex and Trexall methotrexate are used to treat rheumatoid arthritis. Plaquenil is also used to treat or prevent malaria, and to treat symptoms of discoid or systemic lupus erythematosus. Rheumatrex and Trexall are also used to treat some cancers and severe skin diseases such as severe psoriasis. Methotrexate Moderate Hydroxychloroquine may reduce the renal clearance of methotrexate; the exact mechanism of this interaction is unknown. The mean AUC of methotrexate was increased 52% and the mean Cmax was reduced 17% when a single dose of methotrexate was given with a dose of hydroxychloroquine 200 mg oral. Methotrexate–hydroxychloroquine combination therapy may cause lower disease activity in early RA than methotrexate monotherapy. Methotrexate monotherapy as first early RA treatment seems to lead to more treatment intensification. Hydroxychloroquine is used to treat lupus erythematosus and rheumatoid arthritis. It isn’t fully understood how this drug works to treat lupus erythematosus or rheumatoid arthritis. That means you may need to take it with other drugs. It treats malaria by killing the parasites that cause the disease. Methotrexate trexall and hydroxychloroquine plaquenil Compare Hydroxychloroquine vs Methotrexate - Comprehensive., Plaquenil hydroxychloroquine sulfate dose, indications. Plaquenil pain medicationPlaquenil and osteoporosisTaking 4mg plaquenilIs nausea and flu like symptoms normal when taking plaquenilMorrowind aralen ancestral tomb Methotrexate may be sold under the brand names Trexall™, Otrexup ®, Rheumatrex ®, and Rasuvo ®. In addition to being used as a treatment for PsA, methotrexate has been used for decades to treat helps with pain and swelling, and as a DMARD, it can help slow the progression of the most common side effects of methotrexate include nausea, vomiting, and abnormalities. What are Traditional DMARDs? Psoriatic-. Effects of methotrexate and hydroxychloroquine combination.. Plaquenil vs. Methotrexate side effect and effectiveness.. Trexall methotrexate, Barr Laboratories was first developed as a form of chemotherapy and continues to be used as such; however, this drug has gained popularity as an effective DMARD agent. 23 It has been shown to cause certain ocular side effects even at low doses a typical dose may be 2.5mg orally two to three times per week, the most. Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Reduces inflammation and cell replication. Otrexup methotrexate is the first-choice treatment for many types of cancer and arthritis, but it has many side effects. Nov 14, 2017. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment.